Dr. Perry Liu

Our primary physicians

Dr. Dennis

Our primary physicians

Dr Perry

Perry Liu, MD, embodies the convergence of art and medicine that is the essence of aesthetic and reconstructive plastic surgery. His advanced surgical skills not only reflect his background as an artist, but also integrate the artistry of aesthetic surgery, the fundamental surgical principles of reconstructive surgery, and the delicate and precise nature of microsurgery. It takes a combination of multiple skills to be a good plastic surgeon.

Dr. Liu’s skills incorporate multiple disciplines and integrate them into his patients’ journeys of transformation and rejuvenation. With a special interest in Chinese painting, where balance and harmony stages all the elements of a painting, Dr. Liu understands this philosophy and utilizes it to produce more natural results.

International Training

During his 10 years of advanced training to become a cosmetic and reconstructive plastic surgeon, he has trained with world-renowned surgeons in multiple disciplines across the United States and in Asia. These include, but are not limited to, advanced microsurgery, head and neck reconstruction, and breast rejuvenation/reconstruction from Dr. Fu-Chan Wei in Taiwan and Dr. Robert Allen in … …Orleans. He also trained under Dr. Gustavo Colon, a preeminent aesthetic surgeon and former president of the American Society for Aesthetic Plastic Surgery, in New Orleans. Currently, Dr. Liu is in private practice in Los Angeles, CA.

A graduate of Duke University, where he received multiple honors, Dr. Liu continued on to medical school at Emory University in Atlanta, General Surgery Residency at New York Medical College in New York City, a Research Fellowship at Harvard Medical School/Brigham & Women’s Hospital in Boston, a Microsurgical Fellowship at Chang-gung Memorial Hospital in Taiwan, and a Plastic Surgery Fellowship at Tulane University in New Orleans. During the course of his training, he has received multiple awards and honors for his research into advanced wound healing and cancer reconstruction.

Dr. Liu’s fellowship in New Orleans encompassed extensive experiences with breast cosmetic and reconstructive procedures, eyelid surgery, abdominal contouring, and advanced liposuction techniques. As such, he can offer you the latest and most advanced techniques for your rejuvenation. Being well versed in both advanced aesthetic and reconstructive techniques, Dr. Liu’s international training at Chang-gung Memorial Hospital in Taiwan also included the most up-to-date Asian eyelid surgery and nose procedures.

Personal Life

A native of Taiwan, Dr. Liu was educated in the United States and is married to Vivien, his wife of 10 years. They have two adorable children, Adrien and Julien. He and his family are all fluent in Mandarin and reside in Beverly Hills.

Dr Dennis

Many patients choose to have reconstructive breast surgery at the same time as their mastectomy or lumpectomy. An obvious advantage to this is eliminating a second surgery and recovery process. In these procedures, a surgical oncologist or breast surgeon first removes the tumor and then Dr. Liu performs the breast reconstruction portion of the procedure. Upon waking up, the patient has reconstructed breasts, oftentimes better looking than prior to surgery.

Dr. Liu believes in providing patients the highest quality and standard of patient care so he is very selective about who he works with. He is proud to specialize in performing surgery with Dennis Holmes, MD, FACS.

Dr. Holmes is an internationally renowned Breast Surgeon and a noted authority on advanced treatments of breast cancer, including oncoplastic surgerycryoablation (cancer freezing), and radiation therapy. As an authority in the breast cancer community, Dr. Holmes serves in the leadership of several national surgical societies. For example, Dr. Holmes recently led the development of national surgical practice guidelines for the use of preoperative chemotherapy on behalf of the American Society of Breast Surgeons. He is also a Fellow of the American College of Surgeons.

Dr. Holmes is the Chief Breast Surgeon and Medical Director of the Los Angeles Center for Women’s Health. He formerly held the positions of Chief Breast Cancer Surgeon, Breast Cancer Research Committee Co-Chair, and Breast Surgery Fellowship Program Director at the University of Southern California Kenneth Norris Comprehensive Cancer Center. Widely respected by colleagues for his innovative approach to breast surgery, Dr. Holmes is regularly called upon to educate breast surgeons throughout the U.S. and abroad on the optimal treatment of breast cancer.

Dr. Holmes has gained worldwide acclaim for his pioneering research in intraoperative radiotherapy, an innovative type of breast radiotherapy that replaces the usual 5-6 week course of daily breast radiotherapy with a single, 30-minute radiotherapy treatment administered during surgery at the time of lumpectomy. In addition to making breast radiotherapy more convenient, intraoperative radiotherapy reduces radiation side effects on the breast, skin, arm, heart and lung; prevents radiation-related fatigue; and helps women get back to their normal lifestyles much more quickly. Dr. Holmes is also the Principal Investigator of a national clinical trial evaluating the use of cryoablation (tumor freezing) instead of surgery for treatment of breast cancer.

With a commitment to raising the standard of breast cancer care, Dr. Holmes is a strong advocate for individualized or personalized cancer therapy that adapts the level of care to the severity of the cancer, thereby avoiding unnecessary side effects of cancer therapy. For patients, this means better options and better results. What most distinguishes Dr. Holmes is the high level of satisfaction expressed by his many patients. Consistently, patients are relieved to find a breast cancer surgeon who possesses the experience, empathy, and patience to help each woman find a breast cancer solution that suits her physically and emotionally, while also providing the best possible cancer control.

AS A PATIENT OF DR. HOLMES, you can count on having a breast surgeon who:

  1. Understands the emotional impact that breast cancer has on you and your family
  2. Listens patiently to your concerns and questions, and advocates on your behalf on this breast cancer journey
  3. Explains your breast cancer diagnosis and individualized treatment options in a clear and understandable way
  4. Cares about both effectively treating your breast cancer and how you will look and feel after treatment
  5. Offers less burdensome treatment options that reduce long-term side effects
  6. Helps not just restore your health, but helps you achieve better overall health and higher quality of life than you had before your diagnosis of breast cancer.

Most of all, Dr. Holmes believes wholeheartedly that, with proper treatment, most women diagnosed with breast cancer will live a long, fulfilling life, a life richer than they could have ever imagined. Your journey begins today.

Dr. Holmes works with plastic surgeons to plan and perform breast reconstruction. The full range of breast reconstruction options is available. In most cases, breast reconstructions can be started or completed at the time of the mastectomy (called immediate reconstruction), though reconstruction must sometimes be deferred to a later date (delayed reconstruction). Each type of reconstruction has its benefits, risks, and advantages and disadvantages. The right type and timing of reconstruction for you depends on your body size, how much “extra” tissue you have to spare, your overall physical health, your cancer stage, your desired “final” breast size, and your willingness to accept certain risks or disadvantages (e.g., longer length of surgery). Your breast surgeon and plastic surgeon will help you decide what type of breast reconstruction “fits” you best.

You may read more about Dr. Holmes on his website: www.betteroptionsbetterresults.com

Dr. Holmes’ Resume:

Dennis R. Holmes, M.D., Fellow of the American College of Surgeons
Breast Surgeon and Director

Los Angeles Center for Women’s Health
1513 South Grand Avenue, Suite 400
Los Angeles, CA 90015


Tulane University School of Medicine, New Orleans, LA (1991)

University of California San Francisco-East Bay General Surgery Residency Program, Oakland, CA (2002)

University of Southern California Breast Surgery Fellowship Program Los Angeles, CA (2003)


Certifications & Honors:

Active Medical License, State of California (#A68940)

Board Certified by the American College of Surgeons, General Surgery, 2003

2011 & 2010 “Pasadena Top Doc” in Breast Surgery

2009 “Strong Voice Award” for Breast Cancer Advocacy Denise Roberts Breast Cancer Foundation, Los Angeles, CA

2007 County of Los Angeles Outstanding Community Service Award Los Angeles Board of Supervisors Los Angeles, CA



First Surgeon in the World to perform Minimally Invasive Lumpectomy with Intraoperative Radiotherapy, November 9, 2010

First Surgeon in the World to use the Intrabeam Balloon Applicator for delivery of intraoperative radiotherapy. November 9, 2010

First Surgeon in the United States to report performing Minimally Invasive Mastectomy for Breast Cancer October 30, 2009


Recent Positions:

Chief, Breast Section, Los Angeles County + University of Southern California Medical Center, Los Angeles, CA


Assistant Professor of Clinical Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA


Director, University of Southern California Breast Fellowship Program, Los Angeles, CA


Member, Women’s Cancer Program, University of Southern California Norris Comprehensive Cancer Center

Los Angeles, CA


Vice-Chair, Breast Oncology Clinical Research Committee, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA



National Leadership Posts:

American Society of Breast Surgeons, Education Committee and BE-SAP (Breast Education Self-Assessment Program) Committee


TARGIT Trial, National Co-chair, United States Steering Committee


American Society of Breast Diseases, Board-of-Director


National Consortium of Breast Centers, Program Committee


WH2.0 Consensus Conference on Women’s Health Conference Co-Chair

Los Angeles, CA,

Scheduled February 10-12, 2012

American Society of Breast Diseases, 35th Annual Symposium Conference Co-Chair

Dallas, Texas

Scheduled April 13-15, 2012

American Society of Breast Diseases, 34rd Annual Symposium

Program Committee, Session Chair

Dallas, Texas

March 24-26, 2011


Conference Sessions Chaired:

1st Annual IORT Symposium – South California, Co-Chair with Melvin J. Silverstein, M.D.

Newport Beach, CA.

February 16, 2012

International Oncoplastic Breast Surgery Society 2010

Symposium 1 Endoscopic Breast Surgery, Tokyo, Japan

November 25, 2010

American Society of Breast Diseases,

“Best Breast Cancer Papers in the World Literature”

New York City, NY

April 17, 2010

American Society of Breast Surgeons, 11th Annual Meeting

Partial Breast Radiation Workshop, Las Vegas, NV

Co-Chaired with Peter Beitsch

April 30, 2010

American Society of Breast Surgeons, 10th Annual Meeting

General Session-Management Issues/Controversy, San Diego, CA

April 26, 2009

Southern California Chapter of the American College of Surgeons

Annual Meeting

Presiding Officer: Breast Paper Session, Santa Barbara, CA

January 16, 2009

American Society of Breast Diseases, 33rd Annual Symposium Program Committee, Chair: Treatment of High Risk Lesions

Session Co-Chair: Minimally Invasive Surgery in an Interdisciplinary Setting

Chicago, IL

April 2-4 2009


Invited Lectures: National

Holmes DR, Tafra L, Margin Probe Group. Analysis of the impact of intraoperative margin assessment with adjunctive use of MarginProbe® vs. standard of care on tissue volume removed, results from a randomized prospective multi center study. 13th Annual American Society of Breast Surgeons Annual Meeting. Phoenix, AZ. May 4, 2012.

Update of Z11: To Dissect or Not to Dissect. 22nd Annual National Interdisciplinary Breast Center Conference. Las Vegas, NV, March 12, 2012

Challenging Lobular Lesions. 22nd Annual National Interdisciplinary Breast Center Conference. Las Vegas, NV, March 12, 2012

Best Breast Cancer Papers in the World Literature, 2010-2011. American Society of Breast Diseases Annual Meeting, Washington, DC. March 26, 2011

Oncoplastic Breast Surgery: Better for Patient, Better for Surgeon. Kaiser Permanente 7th Annual National Surgical Symposium. Rancho Mirage, CA, April 16, 2011

Advancements in the surgical management of breast cancer. 21st Annual National Interdisciplinary Breast Center Conference. Las Vegas, NV, March 14, 2011

Surgical Oncology for the Non-Surgeon. 21st Annual National Interdisciplinary Breast Center Conference. Las Vegas, NV, March 15, 2011

Targeted Intraoperative Radiotherapy in the Management of Early Stage Breast Cancer. The 16 Annual Multidisciplinary Symposium on Breast Diseases. Amelia Island, FL. February 11, 2011

Intraoperative Radiotherapy of the Breast. The 16 Annual Multidisciplinary Symposium on Breast Diseases. Amelia Island, FL. February 10, 2011

The Best Breast Cancer Papers in the World Literature, 2009-2010. American Society of Breast Diseases, New York City, NY, April 17, 2010.

The American School of Oncology: “Great Debates In Breast Cancer. Should the Sentinel Lymph Node Biopsy be performed before or after administration of neoadjuvant chemotherapy?” (“Before” Position). Debated Ben O. Anderson, M.D., San Francisco, CA., June 19, 2009.


Invited Lectures: Distinguished-International

Intraoperative Radiotherapy in the Management of Early Stage Breast Cancer. National Medical Association Conference. New Orleans, LA. July 31, 2012.

A Breast Surgeon’s Perspective on Fat Grafting As An Adjunct to Breast Reconstruction. Breast Coordinated Care Conference (BC3). Washington, DC. July 21, 2012.

What’s Up with Intraoperative Radiotherapy. Breast Coordinated Care Conference (BC3). Washington, DC. July 21, 2012.

A Case For Not Restaging Patients After Neoadjuvant Therapy Prior to Mastectomy. Breast Coordinated Care Conference (BC3). Washington, DC. July 20, 2012.

Intraoperative Radiotherapy using the Intrabeam System. Breast Coordinated Care Conference (BC3). Washington, DC. July 19, 2012.

How I Do It: Triangle Resection with Crescent Mastopexy. 13th Annual American Society of Breast Surgeons Annual Meeting. Phoenix, AZ. May 6, 2012.

Intraoperative Radiation: Are We Ready for Routine Use? Breast Cancer Society Taiwan, Taipei, Taiwan. September 3, 2011.

Selecting the Patient and the Technique for an Oncoplastic Surgery Approach Canadian Breast Cancer Symposium. Toronto, Canada June 17, 2011.

Intraoperative Radiation: Are We Ready for Routine Use? Canadian Breast Cancer Symposium. Toronto, Canada June 17, 2011.

“Beyond TARGIT: A pragramatic, Risk-Adaptive treatment protocol for Management of Invasive Breast Cancer”. International Oncoplastic Breast Surgery Society 2010. Tokyo, Japan. November 24, 2010.

Selected Publications:

Holmes, D. R. (2015), Intraoperative Radiotherapy of the Breast for Early-Stage Breast Cancer: Ready for Primetime. The Breast Journal. doi: 10.1111/tbj.12375

Holmes DR. Intraoperative Radiotherapy in Breast Conserving Surgery. Journal of Surgical Oncology 2014;110:68–74.

Rivera R, Holmes D, Tafra L. “Analysis of the Impact of Intraoperative Margin Assessment with Adjunctive Use of MarginProbe versus Standard of Care on Tissue Volume Removed,” International Journal of Surgical Oncology, vol. 2012, Article ID 868623, 4 pages, 2012. doi:10.1155/2012/868623.

Rivera R, Smith-Bronstein V, Villegas-Mendez S, Rayhanabad J, Sheth J, Rashtian A, and Holmes DR (Senior Author) Mammographic Findings after Intraoperative Radiotherapy of the Breast, Radiology Research and Practice, vol. 2012, Article ID 758371

Holmes DR. Ongoing consideration of cavity evaluation devices in the treatment of breast cancer. Ann Surg Oncol. 2011:18(7):1809-11.

Holmes DR, Schooler W, Smith R. Oncoplastic approaches to breast conservation. International Journal of Breast Cancer (IJBC 303879), Volume 2011 (2011), Article ID 303879

Diehl KM, Green EM, Weinberg A, Frederick WA, Holmes DR, et al. Features associated with successful recruitment of diverse patients onto cancer clinical trials: Report from the American College of Surgeons Oncology Group. Annals of Surgical Oncology. 6/17/2011:1-7. Epub.

Kelley, LM and Holmes, DR. Tracer agents for the detection of sentinel lymph nodes in breast cancer: Current concerns and directions for the future. Journal of Surgical Oncology. 2010;104(1):91–96.

Holmes DR, Major J, Lyonga D, Alleyne RA, Clayton SC, Clark S. Increasing Minority Patient Participation in Cancer Clinical Trials with the use of Oncology Nurse Navigators. Accepted for Publication. American Journal of Surgery, 2012:203:415-422.

Holmes DR, Baum M, Joseph DJ. The TARGIT Trial: Targeted Intraoperative Radiation Therapy Versus Conventional Post-Operative Whole Breast Radiotherapy after Breast Conserving Surgery for the Management of Early Stage Invasive Breast Cancer (A Trial Update). Am J Surg. 2007;194(4):507-10.

Holmes DR, Silverstein MJ. Minimally Invasive Breast Procedure Clinic: An Innovative Way to Teach Breast Fellows Breast Ultrasound and Ultrasound-Guided Breast Procedures. Am J Surg. 2006;192(4):439-43.

Silverstein MJ, Lagios MS, Recht A, Holmes DR, et al. Image-Detected Breast Cancer: State of the Art Diagnosis and Treatment. J Am Coll Surg. 2005;10(4):586-596.

MacDonald HR, Silverstein MJ, Mabry H, Moorthy B, Ye W, Epstein MS, Holmes DR, Silberman H, Lagion M. Local control in ductal carcinoma in situ treated with excision alone: incremental benefit of larger margins.American Journal of Surgery. 2005;190:521-525.

Holmes, DR. Lobular Neoplasia. In: Surgical Oncology (2nd Ed. Silberman HS, Silberman AW) 2009.

Sheth P, Larson LH, Parisky Y, Holmes DR. Breast Ultrasonography-Performance and Clinical Applications. In Surgical Oncology (2nd Ed. Silberman H, Silberman AW) 2009.

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